Often, this potentiation of channel opening is transient and subsides after several minutes, thus exhibiting acute tolerance (Pietrzykowski et al. 2004, 2008). This type of tolerance can be controlled by changes in the channel’s phosphorylation state (Lui et al. 2004). Our recent data indicate that kinases and phosphatases are involved in alcohol potentiation of the… Continue reading Alcohol Tolerance as You Age: What to Know as You Get Older